Facile Method of Quinoxaline Synthesis Using Phenol as aNew, Efficient and Cheap Catalyst at Room Temperature
Abstarct A simple, highly efficient and green procedure for the condensation of aryl and alkyl 1,2-diamines with α-diketones in the presence of catalytic amount of phenol(20 mo l%) at room temperature is described. Using this method, quinoxaline derivatives as biologically interesting compounds are produced in high to excellent yields and short reaction times.
American Journal of Organic Chemistry 2012, 2(4): 97-104
DOI: 10.5923/j.ajoc.20120204.04